Hormone Therapy May Be Best Defense Against Knee Osteoarthritis
Dr. Kathleen Weaver of Audrain Orthopaedics in Mexico, Missouri is an authority on osteoarthritis and the numerous other elements of the orthopedic subfield of medicine. She is devoted to staying up to date on the very newest research study pertaining to her speciality field. Because of this, she would like you to learn about some amazing new discoveries being made within her field that could substantially impact the nature of exactly how we combat knee osteoarthritis.
A large study posted within the journal Menopause shows that women receiving hormone replacement treatment had a significantly lower prevalence of symptomatic knee osteoarthritis compared with ladies who did not take hormones.
Since oestrogen has an anti-inflammatory effect at high concentrations, it has been hypothesized that hormone changes within women, especially reducing oestrogen levels, may lead to an increase in osteoarthritis following menopause.
One of the most common treatments for knee osteoarthritis include surgery or nonsteroidal anti-inflammatory drugs, both of which are connected with risks such as surgical complications or gastrointestinal conditions.
A number of small studies have actually shown that hormone therapy not only reduces histologic changes in the cartilage involved in osteoarthritis, but it likewise decreases the chronic pain. To date, however, no large-scale studies have analyzed symptomatic knee osteoarthritis and HT.
For the current study, Jae Hyun Jung, MD, Korea University College of Medicine, Seoul, Korea, and colleagues evaluated data from 4,766 postmenopausal women from the Korea National Health and Nutrition Examination Survey (2009-2012). This Korean study has extremely promising results for those with arthritis in Central Missouri.
In the multiple logistic regression models, the knee osteoarthritis odds ratio was 0.70 for the hormone therapy group compared with women who did not take hormone therapy. The authors noted that added research is warranted to adjust for such other variables like age and body mass index.
"Past and current users of hormone therapy had a reduced prevalence of knee joint osteoarthritis, implying that hormone therapy might be defensive against knee osteoarthritis," said JoAnn Pinkerton, North American Menopause Society, Cleveland, Ohio. "This study suggests that excess estrogen taken at menopause might inhibit cartilage damage and decrease knee deterioration seen on x-rays."
If you are concerned about the probability of knee osteoarthritis or have some other concerns regarding orthopedic medicine within Mexico, Missouri, schedule an appointment with Dr. Kathleen Weaver of Audrain Orthopaedics. She possesses the experience and knowledge you need to get your questions answered and collaborate with you to develop a plan for action.